An intensification of human activities takes place on the high seas as a result of significant advances in science and technology, along with growing demand for resources. As the high seas are being degraded, the fisheries depleted and biodiversity increasingly lost, the international community has been witnessing the growing calls for the establishment of marine protected areas (MPAs) as an efficient tool for the conservation and sustainable use of marine biodiversity on the high seas. The thesis examines how international law regulate the use and misuse of MPAs over maritime zones, with a particular focus on the high seas.