This article examines the International Committee of the Red Cross (ICRC) politics and policies in Asia Minor and Greece during the months that followed the end of the war between Greece and Turkey. It is articulated around two moments. The first takes place in Asia Minor during the summer and fall of 1922, right in the midst of the disastrous retreat and final defeat of the Greek Army, which eventually brought to the expulsion of hundreds of thousands Christians. I highlight the rising and relatively suspicious interest of the ICRC for Muslim civilian populations. The second moment takes place in Greece during 1922–1923 and focuses on the range of activities undertaken by the ICRC delegate Rodolphe de Reding Biberegg, when the Greek capital and the rest of the country faced the arrival of hundreds of thousands refugees.